Detalhe da pesquisa
1.
Gating movements and ion permeation in HCN4 pacemaker channels.
Mol Cell
; 81(14): 2929-2943.e6, 2021 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34166608
2.
Reduced Cholecystokinin-Expressing Interneuron Input Contributes to Disinhibition of the Hippocampal CA2 Region in a Mouse Model of Temporal Lobe Epilepsy.
J Neurosci
; 43(41): 6930-6949, 2023 10 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37643861
3.
Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels as Drug Targets for Neurological Disorders.
Annu Rev Pharmacol Toxicol
; 60: 109-131, 2020 01 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31914897
4.
Frequency-Dependent Synaptic Dynamics Differentially Tune CA1 and CA2 Pyramidal Neuron Responses to Cortical Input.
J Neurosci
; 41(39): 8103-8110, 2021 09 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-34385360
5.
Cation leak underlies neuronal excitability in an HCN1 developmental and epileptic encephalopathy.
Brain
; 144(7): 2060-2073, 2021 08 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33822003
6.
Mechanical transduction of cytoplasmic-to-transmembrane-domain movements in a hyperpolarization-activated cyclic nucleotide-gated cation channel.
J Biol Chem
; 293(33): 12908-12918, 2018 08 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-29936413
7.
The Dendrites of CA2 and CA1 Pyramidal Neurons Differentially Regulate Information Flow in the Cortico-Hippocampal Circuit.
J Neurosci
; 37(12): 3276-3293, 2017 03 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-28213444
8.
Structural basis for the mutual antagonism of cAMP and TRIP8b in regulating HCN channel function.
Proc Natl Acad Sci U S A
; 111(40): 14577-82, 2014 Oct 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-25197093
9.
A high affinity switch for cAMP in the HCN pacemaker channels.
Nat Commun
; 15(1): 843, 2024 Jan 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-38287019
10.
TRIP8b regulates HCN1 channel trafficking and gating through two distinct C-terminal interaction sites.
J Neurosci
; 31(11): 4074-86, 2011 Mar 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-21411649
11.
Enhanced excitability of the hippocampal CA2 region and its contribution to seizure activity in a mouse model of temporal lobe epilepsy.
Neuron
; 110(19): 3121-3138.e8, 2022 10 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35987207
12.
Seizures, behavioral deficits, and adverse drug responses in two new genetic mouse models of HCN1 epileptic encephalopathy.
Elife
; 112022 08 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-35972069
13.
Increased seizure severity and seizure-related death in mice lacking HCN1 channels.
Epilepsia
; 51(8): 1624-7, 2010 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-20384728
14.
Sensitivity of HCN channel deactivation to cAMP is amplified by an S4 mutation combined with activation mode shift.
Pflugers Arch
; 458(5): 877-89, 2009 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-19544068
15.
The HCN domain couples voltage gating and cAMP response in hyperpolarization-activated cyclic nucleotide-gated channels.
Elife
; 82019 11 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-31769408
16.
HCN1 channels control resting and active integrative properties of stellate cells from layer II of the entorhinal cortex.
J Neurosci
; 27(46): 12440-51, 2007 Nov 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-18003822
17.
A synthetic peptide that prevents cAMP regulation in mammalian hyperpolarization-activated cyclic nucleotide-gated (HCN) channels.
Elife
; 72018 06 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29923826
18.
The multiple personalities of h-channels.
Trends Neurosci
; 26(10): 550-4, 2003 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-14522148
19.
Regulation of HCN channel surface expression by a novel C-terminal protein-protein interaction.
J Neurosci
; 24(47): 10750-62, 2004 Nov 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-15564593
20.
Binding of the auxiliary subunit TRIP8b to HCN channels shifts the mode of action of cAMP.
J Gen Physiol
; 142(6): 599-612, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24277603